Postdoctoral Position, Non-target Analysis Applications with High Resolution Mass Spectrometry
University of Antwerp - Department of Pharmaceutical Sciences
Applications are invited for a Postdoctoral Research Associate to work under the supervision of Professors Adrian Covaci and Alexander van Nuijs.
Extensive method development and participation in various application projects in the field of:
untargeted and targeted metabolomics;
suspect and non-target screening of environmental contaminants in complex matrices (enviromics);
structural elucidation of (bio)transformation products of xenobiotics.
Explore technical capabilities and applying two-dimensional chromatography coupled to ion mobility and high resolution mass spectrometry (quadrupole-time-of-flight QTOF) in a number of research projects;
Operate, maintain and troubleshoot state of the art instrumentation (Agilent Technologies);
Develop and validate LC-HRMS methods to identify endogenous and exogeneous small molecules in biological matrices;
Participate in the development of analytical and bioinformatics workflows for non-target analysis by HRMS;
Help organize and (co-)supervise work done on high-resolution mass spectrometry for research and services purposes;
Help mentor other group members, including undergraduates;
Coordination, planning, documentation and execution of analyses;
Promote our work at conferences;
Contribute to the generation of scientific publications and external funding bids;
Cooperate with existing and potential customers to plan, execute, discuss and report on small research projects.
Profile and requirements
Hold, or be close to completion of, a PhD in analytical chemistry, mass spectrometry applications in biochemistry, biomedical research, pharmaceutical science or a related area;
Have experience and good knowledge with the safe handling and use of LC-HRMS and the preparation of biological samples (cells, tissues and bio-fluids) for MS-based metabolomics/enviromics;
Have experience in bioinformatics to process HRMS data for statistical analyses;
Have high levels of motivation, good planning, communication and organizational skills;
Have the ability to manage conflicting demands and meet deadlines;
Ability to work effectively both independently and in team, both on projects and as part of a multidisciplinary team;
Possess excellent English communication skills, both written and oral.