Genomics Project Leader
Genomics Project Leader
EMBL-EBI - European Bioinformatics Institute
Hinxton, United Kingdom
We are seeking an experienced project leader for activities and resources supporting model organism genomics at the European Bioinformatics Institute (EMBL-EBI). Mice, rats, zebrafish, flies, worms and yeast are studied extensively by scientists around the world to gain fundamental insights into human biology. The Alliance of Genome Resources (AGR) is a major new initiative to develop shared infrastructure, analysis pipelines and data curation workflows for 6 major Model Organism Databases (MODs) and the Gene Ontology (GO). WormBase, a founding member of the Alliance, is dedicated to providing integrated information on the genetics and genomics of the model organism Caenorhabditis elegans. You will lead a team that acts as the genomics and hub for AGR and WormBase. The team’s responsibilities range from designing and deploying large-scale data integration and genome analysis pipelines, to curating the canonical reference genome and annotation for C. elegans. The team also collaborates closely with the Wellcome Sanger Institute to produce WormBase ParaSite, which uses the Ensembl platform to provide access to hundreds of genomes for parasitic worms that damage human health and food supply.
Your role
You will be a be a member of the EMBL-EBI Eukaryotic Annotation Team and, under the supervision of the Team Leader, will operationally lead our contribution to the Alliance of Genome Resource, WormBase, and WormBase ParaSite. You will work closely with peers at international partner sites to ensure that the overall goals of these projects are met. Your specific responsibilities will include:
- Line management of a team of 5-7 bioinformaticians, developers and curators;
- Leading the development of genomics data analysis and integration pipelines for the Alliance of Genome Resources and WormBase;
- Project management for the provision of parasitic worm genomics data via the Ensembl platform;
- Leadership of the curation effort for the reference genome and annotation for C. elegans and selected other nematodes;
- Engagement with relevant scientific communities;
- Writing publications and reports;
- Representing the project(s) at meetings and conferences.
You have
You will ideally hold a PhD or equivalent in bioinformatics or a related field with demonstrated expertise in genomics. Applicants with a MSc and appropriate experience will also be considered. Specifically, you will have:
- Broad practical knowledge of genomic analysis techniques and tools;
- Knowledge of genome annotation methodologies;
- Practical experience with using databases for modelling complex biological data (knowledge of graph databases will be considered a plus);
- Excellent written and verbal communication skills.
You might also have
The ideal candidate might also have experience with:
- Writing software in Python or Perl;
- Model organism genetics;
- Formal project management principles and techniques;
- Working within international consortia;
- Working with the Ensembl platform.
