We recently succeeded to optically induce hydrodynamic flows within cells and developing embryos (Mittasch et al, Nature Cell Biology 20, 2018).
As a next step we plan to further exploit this technique for the active micro-rheology of phase-separated compartments, as well as precision micro-manipulations of organelles within cells and early embryos (C. elegans and mouse). By this approach we aim to reveal structure-function relationships underlying cellular organization and to gain control of central developmental programs. Long term aims include enhanced clinical diagnostics and early development assistance.
We seek two ambitious postdoctoral researchers with a strong background in biophysics, quantitative biology or related disciplines. Candidates should be familiar with at least several of the following techniques:
Light Microscopy, optics (i.e. optical tweezers), cell culture, C. elegans research, programming (python and/or labview), and quantitative data analysis. Equally important are outstanding creativity and enthusiasm for interdisciplinary science. Excellent English communication skills (spoken and in writing) are required.