Are you passionate about science, full of ideas and innovative potential that drive change and enjoy working in an international, fast-paced environment? Are you motivated by the societal impact of research and seek an opportunity to play an instrumental part in the development of emerging technologies for biology and healthcare? Then the Chair of Biological Imaging (CBI) at the Technical University of Munich (TUM), Germany, and its integrated Institute of Biological and Medical Imaging (IBMI) at the Helmholtz Zentrum Muenchen (HMGU) is the ideal environment for you! CBI is the cornerstone of a rapidly expanding bioengineering ecosystem in the Munich science area; including the Research Center TranslaTUM and the Helmholtz Pioneer Campus, which integrate bioengineering with oncology and metabolic disorders, respectively. CBI scientists develop next-generation imaging and sensing methods to measure previously inaccessible properties of living systems, hence, catalyzing breakthroughs in biology and medicine. Comprising 11 inter-disciplinary laboratories and scientists from more than 25 countries, IBMI offers state-of-the-art infrastructure for innovative research and a perfect environment to accelerate your career. Our research aims to shift the paradigm of biological discovery and translation to address major health challenges of our time and develop the medical solutions of tomorrow. Join our team and be part of our rich and dynamic research culture of enquiry and innovation. CBI researchers come from the top ranks of physics, engineering, chemistry, biology and medicine and our pipeline frequently yields high-impact papers, successful technology spin-offs and commercialization. Our research is regularly featured in major news channels and received broad recognition including several prestigious awards and considerable research funding from national and international sources. We now seek a highly qualified and motivated postdoctoral fellow (f/m/d) to drive the development of advanced reconstruction methods for clinical multispectral optoacoustic tomography (MSOT) projects.
Multispectral Optoacoustic Tomography (MSOT) is a novel medical imaging modality that provides images of biological tissue with optical contrast and acoustic resolution at a depth up to several centimeters. By illuminating biological tissue with laser pulses of different wavelengths and recording ultrasound waves generated via the photoacoustic effect, MSOT can non-invasively detect different chromophores, such as oxygenated and deoxygenated hemoglobin or lipids, without the need for exogenous contrast agents. The underlying reconstruction problem is a highly challenging non-linear and ill-posed inverse problem. Even though the method has demonstrated its clinical value, the reliable quantitative reconstruction of chromophore concentrations from clinical MSOT data has not been achieved so far.
The successful candidate will develop and efficiently implement advanced reconstruction methods for quantitative MSOT in an interdisciplinary team. She or he will also explore methods to integrate ultrasound data acquired in hybrid MSOT and ultrasound (OPUS) systems into the reconstruction. In addition, the candidate is expected to contribute to the institute’s reconstruction software development, and to actively participate in the reconstruction and analysis of clinical MSOT data, provided by a team of trained clinicians. In particular, exploiting the benefits of data-driven methods in both reconstruction and data analysis are of great interest for MSOT and OPUS. The candidate can build on existing methods and software developed at the institute.
The successful applicant must have the following: