Postdoctoral Training Fellow
The Francis Crick Institute
London, United Kingdom
This is a full-time, fixed term position for 4 years on Crick Terms & Conditions of Employment.
This role will be pivotal in ensuring continuation of research within a Wellcome Trust funded program on the functions of the aryl hydrocarbon receptor in immune cells. The post holder will be part of a team of researchers in the Stockinger lab.
To find out more about the research conducted please follow the link provided: https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/gitta-stockinger/.
The Postdoctoral Scientist will carry out research on physiological roles of the aryl hydrocarbon receptor (AhR) in the immune system focusing on dendritic cells in the gut and lung within a team that investigates immune responses at barrier sites.
The post holder will carry out independent research within a team to study AhR functions.
Specific objectives will include, but not be limited to:
- The post holder is expected to work within a team that carries out research on functional roles of AhR at barrier sites such as the skin, lung and intestine and studies the influence of environmental triggers in health and disease;
- The post-holder will be responsible for designing, performing, analysing and interpreting experiments to investigate the role and regulation AhR in mucosal immune cells with a particular focus on dendritic cells.
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a brand new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under a single roof in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; to developing emerging talent and exporting it the rest of the UK; to public engagement; and to helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:
- A PhD in immunology;
- Experience working with mice and in vivo techniques such as isolation of rare cell types and preparation of RNA for transcriptomic analysis, genetically modified mice and infection models;
- Experience in general molecular biology techniques;
- The postholder is expected to be creative and motivated, conscientious and able to work independently, but also to interact well within the team. Excellent record keeping and ability to communicate well in English are also essential;
- Demonstration of scientific ability and excellence by means of authorship (first author) peer reviewed publications in internationally recognized scientific journals.
- Strong experience in mucosal immunology;
- Basic skills in bioinformatics analysing of RNAseq and ChIPseq data.
Postdoctoral Training Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and guide PhD students in their research. The ability to work in a team is essential.
Please note: all offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.